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Google DeepMindโ€™s latest AI breakthrough is rewriting the rules of science. In just minutes, this new AI accomplished what took human scientists years of research! ๐Ÿคฏ

From cracking complex protein structures to solving unsolvable math problems, DeepMind is pushing the limits of what's possible with AI.

๐ŸŒ What is this new AI model capable of?
๐Ÿงฌ How is it changing science forever?
โšก Could this be the start of a new era in discovery?

Watch this video to uncover how DeepMind's powerful technology is revolutionizing scientific progress โ€” and what it means for the future of humanity.

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๐Ÿ” Dive into the AI thatโ€™s changing the world โ€” one breakthrough at a time.
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Transcript
00:00What if AI could not only predict how proteins interact, but actually create new ones to fight
00:07diseases like C19 or cancer? In this video, we're exploring two groundbreaking AI models,
00:12Alpha, Proteo, and Orb, that are reshaping everything from drug discovery to material
00:17science. And before we get started, take a second to subscribe and stay ahead of the curve on all
00:22the latest AI trends and updates. Alright, you know how proteins are like the workhorses of
00:27our bodies, right? They do everything from helping our cells grow to keeping our immune systems
00:32running smoothly. And of course, they're at the core of pretty much every biological process.
00:37But here's the catch. These proteins don't just do their jobs in isolation. They interact with other
00:43proteins. Think of it like a key fitting into a lock. One protein binds to another. And that's how
00:50all these critical functions happen inside our cells. Now, thanks to things like AlphaFold, we
00:55already have a pretty solid understanding of how proteins interact. AlphaFold helps us predict what
01:00these interactions look like, which has been huge for science. But here's the kicker. While AlphaFold
01:05is awesome at figuring out how proteins connect, it doesn't create new proteins that could manipulate
01:11or influence these interactions. And that's where the real magic comes in, guys. Enter Alpha Proteo by
01:17Google DeepMind. This is the new AI system we're talking about today. It doesn't just predict
01:22interactions. It designs entirely new proteins that can bind to specific target molecules.
01:28And why is that important? Well, these designed proteins, also called binders, can speed up all
01:34sorts of research, from drug discovery to figuring out how diseases work, to making crops more resistant
01:40to pests. Now, let's break this down. When you want to create a protein that binds tightly to a target,
01:45like, say, a virus protein that causes C19, it's not easy. Traditional methods are super slow.
01:52You have to create binders in the lab, test them, optimize them, then test them again. It's like an
01:59endless cycle of trial and error, which, as you can guess, takes forever. But with Alpha Proteo,
02:04we're talking about a major shortcut. This AI system has been trained on a ton of protein data.
02:10We're talking about data from the protein data bank and more than 100 million predicted structures
02:15from AlphaFold. So yeah, it's learned a thing or two about how proteins interact.
02:19Now, if you give Alpha Proteo the structure of a target protein and tell it where you want the
02:25protein to bind, it can design a binder protein that fits that target almost perfectly. That's like
02:31handing it the blueprint for a lock and having it design the perfect key. And it works on all kinds
02:37of proteins. Cancer-related proteins, proteins from viruses like SARS-CoV-2, yes, the one involved in the
02:44lockdown era, the C-19, and even proteins tied to autoimmune diseases. So far, the results are
02:51pretty mind-blowing. In fact, Alpha Proteo generated binders for seven different target proteins. And
02:57here's the kicker. They tested these proteins in the lab and the AI-designed binders worked like a
03:01charm. I'm talking about three to three hundred times better binding strengths than the best existing
03:07methods. Insane, right? For example, let's take VGFA, which is a protein linked to cancer and diabetes
03:14complications. For the first time ever, an AI system, Alpha Proteo, designed a protein binder
03:21that successfully binds to VGFA. That alone is a huge milestone. And it's not just one-off successes.
03:28Let's take another protein, BHRF1, which is a viral protein. In the lab, 88% of Alpha Proteo's
03:35candidate binders actually bound to BHRF1 successfully. And get this, Alpha Proteo's
03:40binders on average are binding 10 times stronger than any of the current best designs.
03:46Now, one of the most hyped targets was the SARS-CoV-2 spike protein, the very same spike that
03:52helps the virus get into our cells. And yeah, Alpha Proteo nailed it. Not only did it design binders for
03:58this spike protein, but those binders were tested by some top research groups like the Francis Crick
04:04Institute, and they confirmed the binders were legit. These binders even managed to block the virus
04:09and some of its variants from infecting cells. So we're looking at something that could potentially
04:15help in virus prevention. Now, obviously, this tech isn't perfect yet. For example, Alpha Proteo couldn't
04:21design a successful binder for TNFA, which is a protein associated with autoimmune diseases like
04:28rheumatoid arthritis. But to be fair, TNFA is known to be a beast in terms of difficulty.
04:34The team picked it on purpose to test the limits of the system. So it's not all bad news. In fact,
04:39it's a sign that they're pushing the system to improve. And while strong binding is critical,
04:43it's just the first step in using these proteins for real-world applications, like drug design.
04:49There's still a ton of bioengineering work to do, but Alpha Proteo has already knocked out one of the
04:54toughest parts. Now, the team behind Alpha Proteo is working with scientists across the world to make
05:00this system even better. And they're thinking responsibly about biosecurity. That means making
05:06sure this powerful tech is used for good, like developing treatments and cleaning the environment
05:11rather than, you know, any shady stuff. And if you're wondering where this is going, well, they've
05:15already teamed up with groups like the Nuclear Threat Initiative to set up best practices. So the tech is
05:21evolving, but with caution, which is honestly a relief. Looking ahead, they're also exploring drug
05:27design applications with a company called Isomorphic Labs. And they're actively working
05:32on improving the algorithms to make the system even stronger and more versatile. And they're not
05:37just doing this in a vacuum. They're collaborating with experts in machine learning, biochemistry,
05:42and structural biology. So the future of protein design, yeah, it's looking pretty exciting.
05:47All right. Now there is another thing I'm seriously hyped about, and it's actually a massive
05:51breakthrough in AI and material science. We're talking about ORB, the latest and greatest AI
05:56model for simulating advanced materials. It's open source, it's blazing fast, and it's leaving big
06:02names like Google and Microsoft in the dust. If you're into AI, energy, or just cutting-edge tech,
06:08you're going to love this. So let me break it down for you. Imagine you're a scientist working on
06:13materials for, say, better batteries or solar panels, things that are crucial for the energy
06:17transition, right? Well, here's the thing. To design these super-efficient materials,
06:22you need to know exactly what's happening at the atomic level. We're talking about how atoms and
06:28molecules are interacting, what makes certain materials conduct energy better, or how you can
06:32tweak them to be more efficient. But, and this is the tricky part, actually seeing or simulating
06:38what's happening inside these materials is insanely hard. Traditional methods for simulating this stuff,
06:43they're slow, costly, and often involve simplifying things so much that you're not even getting an
06:50accurate picture. It's like trying to watch a 4K movie on dial-up internet. It's just not happening. And
06:56that's where AI comes in, giving us a new way to look at these materials with way more detail, without
07:02waiting forever. This brings us to ORB, the model we're talking about today. Built by a company called
07:08Orbital. ORB is designed to simulate materials at the atomic level faster and more accurately than
07:15anything else out there right now. And get this, it's based on a bigger AI model they've been working
07:20on internally called Linus. So basically, they've been fine-tuning this thing for a while now, and it's
07:25paying off in a huge way. Now, ORB isn't just faster than the competition, it's five times faster than the
07:31best alternatives for large-scale simulations. That's a huge leap forward. And we're not just talking about
07:36beating random models either. ORB is outperforming Google's and Microsoft's models when it comes to
07:42accuracy and speed. And here's where things get even more exciting. They've open-sourced it.
07:47Yup, it's free for non-commercial uses in startups. So anyone looking to develop new materials can jump
07:52in and use this tech. You can even go to their GitHub right now and check out the full technical
07:58breakdown. Now, let me pause here for a second to explain why this is so important. We're in the middle
08:04of a massive shift toward renewable energy, and materials are at the heart of that. Whether it's
08:09batteries for electric cars, solar panels for homes, or semiconductors for basically all of our tech,
08:14the materials we use need to get better, more efficient, longer lasting, you name it. And the
08:20faster we can simulate and design these materials, the faster we can make them a reality. ORB is a tool
08:26that's going to accelerate that process in a big way. Now, if you're wondering how ORB came to be,
08:32it all ties back to this foundation model I mentioned earlier, Linus. The team at Orbital
08:37has been training and refining Linus from the ground up. ORB is like Linus on steroids,
08:43specifically fine-tuned for advanced material simulations. They've got a whole blog explaining
08:48the key elements if you want to dive into the technical side, and they've got even more info
08:53coming soon. So yeah, this isn't some random new AI model. It's been a long time coming. And can we just
08:59take a second to appreciate the team behind this? This isn't some massive tech giant with endless
09:04resources. We're talking about a small, tight-knit group that's competing with the biggest names in
09:08AI, Google, Microsoft, and so on. It's proof that even in an era where it seems like only the giants
09:14can make big moves, a scrappy, motivated startup can still come out on top. So there you have it.
09:20ORB, the fastest and most accurate AI model for advanced material simulations, is out there.
09:25And it's free to use for non-commercial purposes. I can't wait to see where this goes.
09:30As always, drop your thoughts in the comments. Are you as excited about this as I am?
09:35Smash that like button, and don't forget to subscribe for more deep dives into AI and tech.
09:40Thanks for watching, and I'll see you in the next one.
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