In February, Silverstein, who had just turned 50, received a brutal diagnosis. The six-time Midas List member had an aggressive form of Parkinson's disease linked to a mutation of a gene called GBA, which makes a key enzyme that functions as something of a garbage collector for the body's cells. GBA-associated Parkinson's is rare, afflicting about 50,000 people in the United States; it's considered an advanced and deadly form of the disease.