http://www.youtube.com/watch?v=PtqbrxB_S_4

In this video I will discuss
Modafinil Synergy and Interactions
Synergy is the joint action
of two or more agents that
Produces a combined effect greater than the sum of their individual effects
Modafinil Synergy:
Modafinil is synergistic with Yohimbe
Yohimbine a stimulant and aphrodisiac from the plant Yohimbe
Also enhances norepinephrine activity, but you should be careful because
This combination can cause a dangerous increase in heart rate and blood pressure
Modafinil is also synergistic with coffee and caffeine, but the same warning applies
Interactions of Modafinil:
Birth control pills have decreased effectiveness when combined with Modafinil
The mechanism is that Modafinil upregulates (increases the quantity) of an enzyme
Which breaks down the
contraceptive hormones
Thus, higher doses of birth control pills may be needed
400mg/day of Modafinil for a month significantly reduced levels of estradiol and
Norgestimate in a study of 16 women
Modafinil also interacts with Opiates
(including Methadone)
The action of these drugs can be substantially shortened
Concomitant use of opiates and Modafinil results in the formers decreased effectiveness
If you suffer from epilepsy, or serious hepatic or renal disorders,
Modafinil can be contraindicated to you
Another thing to remember is that in some countries
Modafinil is considered a doping agent and a prohibited stimulant
Long-term use has also been associated with instances of elevated liver enzymes
Thus, if you plan to use Modafinil for an extended period of time,
You should have your liver function tested to establish a baseline,
And then retest after 3 months and again every 6 months thereafter to spot changes
If abnormalities appear, reducing the dose or stopping the drug should permit a return to normal
One last but very important thing
Combining Modafinil with
Alcohol is a very bad idea
At least 24 hours should pass between your last Modafinil dose and Alcohol use
In most situations,
I would advise against using Modafinil
But I believe many will try it anyway so you might as well be correctly informed
In this video we have discussed
Modafinil Synergy and Interactions

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