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In a surprising report, grapefruit juice has serious side effects with medication.
Grapefruit juice can cause dangerous and even deadly side effects when it is combined with certain drugs.
Scientists from the University of Western Ontario found that the number of drugs that interact with grapefruits was found be much higher than they previously thought.
17 different drugs were believed to have negative interactions with grapefruits, but now that number has gone up to 43.
Grapefruits have certain chemicals that change how your body absorbs the drugs before they enter the bloodstream and take effect.
Some of the potential side effects from a combination of grapefruit and any of the drugs on the list include heart problems, kidney failure, blood clots, muscle breakdown and difficulty breathing.
Some common medications such as Lipitor have shown serious interactions when they are mixed with grapefruits or grapefruit juice.
Professor Paul Doering of the University of Florida Pharmacy Department said: "People know that drugs react with drugs, but fewer are aware of drug-food interactions. Health professionals need to learn as much as they can about this. Undetected there are very serious adverse effects."