Spello is an ancient town and comune (township) of Italy, in the province of Perugia in east central Umbria, on the lower southern flank of Mt. Subasio. It is 6 km (4 mi) NNW of Foligno and 10 km (6 mi) SSE of Assisi.
The old walled town lies on a regularly NW-SE sloping ridge that eventually meets the plain. From the top of the ridge, Spello commands a good view of the Umbrian plain towards Perugia; at the bottom of the ridge, the town spills out of its walls into a small modern section (or Borgo) served by the rail line from Rome to Florence via Perugia.