Unrest follows Alison Blanchard, who is studying to become a physician. Her journey begins in her Gross Anatomy class where she must confront rows of cadavers and her own fear of mortality. When her cadaver is revealed, Blanchard senses a strange presence in the lab. Her jaded professor chalks her feelings up to first year jitters, but her suspicions increase when a friend is found dead in the basement. Now, Blanchard must find out the truth about her mysterious cadaver before its angered spirit wreaks further vengeance on those who dared to disturb its body.