Monsters have blown up and escaped from a top secret Psychic Research facility and stolen one of the lovely lab assistants as well. Dr. Knavik gives Lucia his precious ESP Booster to save her twin sister Cecile.
By collecting various items on her travels, the ESP Booster grants Lucia various powers (kind of like Mega Man...) to destroy her enemies and also navigate quickly through levels. This is exacerbated for the author by poor hit detection and finicky input control. Input is only allowed one time every four frames. Nevertheless the end result is a fast paced and varied movie.
This is a tool-assisted speedrun, made on an emulator, using frame-by-frame shooting, savestates, and rerecords to overcome reaction time and human error. As such, it is purely a form of entertainment, and is not designed to show skill.