Age-Related Macular Degeneration and Underlying Heart Damage
  • 10 months ago
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New Study Reveals Connection Between Age-Related Macular Degeneration (AMD) and Underlying Heart Damage

According to a recent study from the New York Eye and Ear Infirmary of Mount Sinai, patients with a particular type of age-related macular degeneration (AMD), a major cause of blindness, are also very likely to have underlying heart damage. Heart failure, heart attacks, advanced valve disease and/or carotid artery diseases are all potential issues linked to those with a specific form of AMD – subretinal drusenoid deposits (SDDs).

What is Age-Related Macular Degeneration (AMD)?

Age-Related Macular Degeneration (AMD) is a chronic and painless disease of the macula. A region known as the macula lies at the centre of the retina, at the back of the eye.

It occurs when the macula, the area of the eye that regulates precise, straight-ahead vision, suffers damage with age. Central vision gradually declines; however, the peripheral vision remains unaffected. The inability to see faces well and read or watch TV are all impacted by this loss of central vision. However, AMD alone does not cause complete blindness (black blindness).

Some persons with AMD experience very slow progression and no visual impairment. Others may see a quicker progression of AMD, which might impair vision in one or both eyes.

In Australia, it is the most prevalent macular condition. Half of all blindness and severe vision loss in this nation are caused by AMD.

Read more about risk factors, symptoms and diagnosing AMD.

SDDs and drusen are the two primary forms of deposits found in the retinas of persons with age-related macular degeneration.

Small, yellow cholesterol deposits known as drusen, which develop behind the retinal pigment epithelium (RPE), are one of the main symptoms of early AMD. They may rob the retina of blood and oxygen, which might result in blindness. The production of drusen can be slowed down with the right vitamin intake.

Subretinal drusenoid deposits (SDDs), the other primary type of early AMD, are less well known and must be found with sophisticated retinal imaging. These deposits, which accumulate above the RPE and immediately below the light-sensitive retinal cells, are made up of a distinct type of cholesterol and where the damage and loss of vision occur. SDDs have no recognised treatments.

Are you at Risk?

Mount Sinai doctors and researchers discovered that SDDs were more prevalent in individuals with cardiovascular illness or stroke. The results of the ground-breaking study were published in BMJ Open Ophthalmology.