- Manchester is the state's commercial and industrial leader, as well as its largest city and the home of nearly 10 percent of its population. Manchester rebuilt itself as a commercial and industrial center by diversifying industries. Today it is home to a melting pot of high tech companies, banks, business services enterprises, retailers, manufacturers and health care professionals. Commerce is just one part of Manchester's appeal. The city is also the focal point of the state's cultural community and home to many of the region's eight colleges and universities. Cultural institutions such as the Currier Gallery of Art and Palace Theatre join with the new Verizon Wireless Arena and outdoor concert venues to attract world-class performers and exhibits to the city.