The Brain That Wouldn't Die, also known as The Head That Wouldn't Die, is a 1962 science-fiction/horror film directed by Joseph Green and written by Green and Rex Carlton. A scientist develops a means to keep human body parts alive. When he unexpectedly must use his discovery on someone close to him, events do not go as planned.
Dr. Bill Cortner is a successful scientist with a beautiful fiancée named Jan Compton. After a horrible car accident decapitates Jan, Dr. Cortner collects her severed head and rushes it to his laboratory, where he revives it and manages to keep it alive in a liquid-filled tray.
Dr. Cortner now decides to commit murder in order to obtain an attractive new body to attach to his fiancée's head. As he hunts for a suitable specimen, Jan begins to hatch some murder plans of her own. Filled with hatred for Cortner because he won't let her die, she communicates telepathically with a hideous mutant in the laboratory cell, telling it to kill the scientist.