Licking diabetes with lizard spit?

Developed by Amylin Pharmaceuticals and Eli Lilly, exenatide is a synthetic version of a hormone in the saliva of Gila monsters, a lizard that eats only four times a year. When it eats, it secretes the hormone, similar to GLP-1 in humans, to activate insulin production in the pancreas.

Exenatide is the furthest along in development of several drugs that focus on GLP-1, an intestinal hormone that is released after a meal. The drug will be submitted to the Food and Drug Administration this summer and, if approved, could be available next year.

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