Katie Holmes' Biggest Career Mistake?

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Dana Delany as Carrie Bradshaw? Matthew Broderick as Walter White? Pamela Anderson as Scully? Molly Ringwald as the ultimate Pretty Woman? Yeah, we know none of this sound right - that's because these actors passed on these iconic, award winning roles! But we have one that is mind boggling. Katie Holmes in an orange jumpsuit as the bi-sexual, drug smuggling prisoner Piper Chapman! Apparently she didn't think OITNB was going to be a hit and passed when she was offered the groundbreaking role. During a recent panel for the Netflix show, the cast had some fun with the almost-casting news!