Ys: The Ark of Napishtim (イースVI -ナピシュテムの匣- Īsu Shikkusu -Napishutemu no Hako-?, Ys VI: The Ark of Napishtim) is a Japanese action RPG developed and published by the Nihon Falcom Corporation, and the sixth installment in the Ys video game series. It was first released in 2003 for Microsoft Windows-based personal computers. Not counting the Eternal/Complete remakes of Ys I & II, it was the first new Ys game released by Falcom in eight years.

Ys was ported to the PlayStation 2 in 2005 and to the PlayStation Portable in 2006 by Konami for worldwide release. It was the first English release of the series since Ys III: Wanderers from Ys.