Colorado Buffaloes vs. USC Trojans Pick Prediction College Football Odds

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The USC Trojans will hit the road in PAC 12 conference action as they face the Colorado Buffaloes in an NCAA college football game set for Saturday night.

Kick off time from Colorado is set for 9:30PM Eastern Time with national television coverage provided by the PAC 12 Network.

The college football odds from this contest have the road tam USC Trojans favored by -22 points.

USC improves to 8-3 on the year following a 20-17 home victory last week to the Stanford Cardinal as a +3 ½ point underdog. The total came in at under 45 points.

The Trojans offense produced 311 yards with just 23 yards rushing for one yard per carry. Cody Kessler hit on 25 of 37 passes for 288 yards with a touchdown. The team turned it over once and took three from Stanford. The Trojans defense gave up 337 yards to the Stanford offense with 210 running for 6 yards per rush.

Colorado improved to 4-6 following a 41-24 home victory last week to the California Golden Bears as a -1 point wagering favorite. The game total landed at under 67 points. The Buffaloes went up 24-10 at the half.

The Colorado offense produced 485 yards with 121 running for 3 yards per rush. Sefo Liufau hit on 23 of 36 passes for 364 yards with three touchdowns and one pick. The Buffaloes on defense gave up 411 yards to California with 197 yards running for over 5 ½ yards per run attempt.

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