Boston College traveled to Wake Forest with 1st place in the Atlantic Division on the line. Kevin Marion had an 81-yard TD run and Patrick Ghee intercepted a pass in the end zone with just under a minute to play as #22 Wake Forest def. #16 Boston College 21-14. BC QB Matt Ryan set career highs by completing 40-of-57 passes for 402 yards, but also threw two interceptions. The Demon Deacons would go on to win the 2006 ACC Championship.